Curing Cancer Newsletter - December 2023
29 December 2023
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This abstract was presented at a recent conference held by the American Association of Cancer Research, the National Cancer Institute and the European Organisation for Research and Treatment of Cancer. These conferences provide an opportunity for physicians and scientists to present their research.
Read more at https://natpernick.substack.com/p/the-scientific-process-advancing
Bile duct cancer
This is part of our series on cancer from a pathologist's perspective.
Bile duct cancer, also called cholangiocarcinoma, is typically discussed with liver cancer because the bile ducts originate in the liver. However, the cells of bile duct cancer resemble bile ducts and not liver cells, and these cancers behave differently from liver cell cancer (also called hepatocellular carcinoma).
Read more at https://natpernick.substack.com/p/bile-duct-cancer
Extrahepatic tumor contains small, dispersed glands and single cells in a haphazard appearance, contributed by Raul S. Gonzalez, M.D.
Cell migration in children and adults
It is important to understand physiologic (normal) cell migration because this process is hijacked by metastatic cancer cells.
Read more at https://natpernick.substack.com/p/cell-migration-in-children-and-adults
See also Cell migration in the embryo and fetus.
White blood cells (purple cells with granules) migrate from blood vessels into infected tissues to destroy bacteria (oval yellow particles with hairlike projections)
Liver Cancer
Liver cancer combined with intrahepatic bile duct cancer is the #6 cause of cancer death in the U.S. (after lung, colon, pancreas, breast and prostate cancer), with 29,380 deaths projected in 2023 (19,000 in men, 10,380 in women).
Liver cancer typically refers to primary liver cancers, i.e. cancers that originate in the liver and resemble liver cells. About 80% of primary liver cancers are liver cell cancer (hepatocellular carcinoma). The rest are usually cancer of the intrahepatic bile ducts (cholangiocarcinoma).
See the rest of the post at https://natpernick.substack.com/p/liver-cancer
Liver cell cancer (hepatocellular carcinoma), by Irene Y. Chen, M.D.
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